Nicotinic相关论文
Neuroprotective effect of the ethanol extract of Artemisia capillaris on transient forebrain ischemi
Artemisia capillaris Thunberg is a medicinal plant used as a traditional medicine in many cultures.It is an effective re......
Nicotine Exposure Recruits Glutamate Receptors to Postsynaptic Sites on Hippocampal Neurons in Cultu
Cholinergic neurons project throughout the nervous system and activate nicotinic receptors to modulate synaptic function......
Mesenchymal stem cells as a potential therapeutic tool to cure cognitive impairment caused by neuroi
An established contribution of neuroinflammation to multiple brain pathologies has raised the requirement for therapeuti......
The distributions of nicotinic acid (NA) between water and trialkylamine (N235) dissolved in n-octanol was studied. The ......
Three new Cu(Ⅱ)-Ln(Ⅲ) heterometallic coordination polymers constructed from quinolinic acid and nico
Three new Cu(Ⅱ)-Ln(Ⅲ) heterometallic coordination polymers based on two N-heterocyclic carboxylic ligands, {[LnCu(L1)2......
A heterometallic metal-organic framework,Ag In(nicotinate)4·1.5DMF,was obtained from the reaction of nicotinic acid,Ag ......
We report the fabrication and characterization of a magnetically recyclable Fe_3O_4@Nico@Ag catalyst for reduction react......
目的近几十年,肌肉型乙酰胆碱受体(nicotinic acetylcholine receptors,nAChRs)成为神经生理学、药理学、药物设计及相关疾病研究......
AIM:To assess the effect of different hypolipidemic treatment strategies on glycemic profile in mixed dyslipidemia patie......
Synthesis and Crystal Structure of 1-[(1-Phenyl-4-cyano)pyrazol-5-yliminomethyl]-2-nitroiminoimidazo
The title compound 1 [(1 Phenyl 4 cyano)pyrazol 5 yliminomethyl] 2 nitroiminoimidazolidine 2 (C 14H 14N 8O ......
An effective prediction pharmacophore model(RMS=0.634,Correl=0.893,Weight=1.463,Config=11.940)was success- fully obtaine......
本实验采用膜片箝技术观察了神经生长因子分化 5～ 10 d的大鼠肾上腺嗜铬细胞瘤 (PC12 )细胞上烟碱受体离子通道电流。在全细胞膜片......
Nicotinic acid was synthesized from 3 methylpyridine with potassium dichromate as the oxidant. The reaction conditions,......
The upregulation of transforming growth factor-β plays animportant role in the induction of nasal to
Nasal administration of nicotinic acetycholine receptor (AChR) to Lewis rats prior to myflsthenogenic immunization with......
A novel method for synthesizing magnetically recyclable nanocatalyst Fe3O4@Nico@Cu(Nico = nicotinic acid) was introduced......
Synthesis of 2-[~(18)F]fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine as a radioligand for imaging nico
Nicotinic acetylcholine receptors (nChRs) are involved in the various pharmacological effects or disease states. In orde......
Study of apoptosis pattern of dopaminergic neurons and neuroprotective effect of nicotine in MPTP mo
Objective: To investigate the apoptosis of dopaminergic neurons and the protective effect of nicotine in 1-methyl-4-phen......
Previous studies have demonstrated that the cholinergic system,via nicotinic receptors,regulates intracellular free calc......
Inhibitory effects of synthetic cannabinoid WIN55,212-2 on nicotine-activated currents in rat trigem
Cannabinoid and nicotinic acetylcholine receptors are strongly associated with algesia.Previous studies in our laborator......
Nerve agents are organophosphorus compounds (OPs) which are misused as chemical warfare agents for military and terroris......
This short communication discusses an interactive brain mapping study using connectomics technique on an important neuro......
Therapeutic potential of α7 nicotinic receptor agonists to regulate neuroinflammation in neurodegene
Neurodegenerative diseases, such as Alzheimer’s, Parkinson’s and Huntington’s diseases, are all characterized by a co......
目的：研究毒扁豆碱阻断交感节神经元烟碱受体的作用机理．方法：以培养的新生大鼠颈上交感节神经元为标本，使用全细胞膜片箝技术，观察毒扁......
首先自gentiana kirilowi中提出生物鹼gentianine,並初步確定其構造式。此後,不同作者自D.Azureus及G.Pevmonanthe分離出相同生物......
目的:研究siRNA干扰尼古丁乙酰胆碱受体α5(cholinergic receptor nicotinic alpha5,CHRNA5)基因表达后对尼古丁促人肺癌A549细胞......
BACKGROUND: Experimental autoimmune myasthenia gravis (EAMG) and anti-AchR antibody of human myasthenia gravis are the s......
Quninuclidinyl-benzilate (QNB) has long been recognized as a competitive antagonist of muscarinic acetylcholine recepto......
Nicotinic and muscarinic receptors are distinctively different, and belong to ion channel-gated and GTP binding protein......
Aim:To explore the cell specific existence of α9 AChR in the vestibular type Ⅱ haircells(VHC Ⅱ)of rats.Methods:To de......
A series of new symmetrical and asymmetrical aliphatic tertiary amines and nicotinic acid derivatives synthesized as hyd......
Tobacco-specific Carcinogen 4-(Methylnitrosoamino)-1-(3-pyridyl)-1-butanone(NNK) Activating ERK1/2 M
Cigarette smoking is correlated with the development of various cancers. 4-(Methylnitrosoamino)-1-(3-pyridyl)-1-butanone......
AIM: To investigate the effect of nicotine on β_1-adrenergic receptor (β_1-AR) in the hippocampal slice of rat. METHO......
Previous studies have demonstrated that muscarinic,and nicotinic receptors increase free Ca2+ levels in the facial nerve......
Since being develoPed apProximately 20 years ago,highthroughPut screening(HTS)has beeome one of the key teeh-n iques use......
Aim: To develop a homogeneous high-throughput screening (HTS) assay based on scintillation proximity assay (SPA) techno......
Cytochrome c is a kind of electron transfer carrier in the living organisms. In recent years, many electrochemists have......
Identification of α7 nicotinic acetylcholine receptor on hippocampal astrocytes cultured in vitro an
The present study found expressions of α7 nicotinic acetylcholine receptor on hippocampal slices and hippocampal astroc......
Seven new Schiff bases, which are 4,4,4-trifluo-ro-1-(2-thienyl)-1-butanone-3-Z, Z =-thioseraicarbazone (a); -thiocarbo......
该文研究了尼古丁型乙酰胆碱受体(nicotinic acetylcholine receptors,n ACh Rs)不同亚单位在大鼠大脑星形胶质细胞的表达情况。分......
Chromium is an essential trace element for mammals[1-3].Diabetes is a chronic disease with major health consequence.Stud......
The crystal structure of the title compound (C17H19Cl2N2O3P, Mr = 401.21) has been determined by single-crystal X-ray d......
In an electrolytic cell with a proton exchange membrane, nicotinic acid was synthesized at the PbO_ 2 anode. The relatio......
A pair of derivatives of tetrameric N-methylpyrrole polyamide were synthesized in order to develop a new method for the ......
The copper(II) complexes of pyridine-3-carboxylic acid (nicotinic acid) and pyridine-2-carboxylic acid (isonicotinic aci......
A novel Ag(I) complex AgH(Nifa)2 1 (C26H17AgF6N4O4, Mr = 671.31) was synthe- sized through hydrothermal reaction of Ag2S......
Hydrothermal Synthesis,Crystal Structure and Spectroscopic Investigations of [Y(C_6NO_2H_5)_3(H_2O)_
A new heterometallic 4f-3d complex [Y(C6NO2H5)3(H2O)2]n(1.5nZnCl4)·nH2O(1), was synthesized via a hydrothermal reaction......
